Jack Greene

Jack Greene is a dedicated professional with over 25 years of experience focused on drug substance, drug product, and CMC regulatory teams at various organizations.

Jack created and led the CMC function of CinCor Therapeutics, a clinical-stage biotech, through the complex manufacturing process of baxdrostat, culminating in its acquisition by AstraZeneca. Prior to CinCor, he served as Head of CMC at Anagram Therapeutics, and held positions at Allena Pharmaceuticals, Alcresta Therapeutics, Alnara (acquired by Eli Lilly & Co), Altus Pharmaceuticals, Alkermes, Genzyme, and Serono.

Jack has demonstrated key skills in CMC regulatory, process development of both NCE/NME and biologics drug substances, and formulation development of oral, parenteral, and inhalation drug products. He has successfully managed analytical development/QC and characterization, integrated commissioning and qualification of new manufacturing plants, and the design of integrated plant-wide process control systems. His strategic design, implementation, and validation of enterprise-level computer systems, including LIMS, SCADA, ERP/MRP, eQMS, and CMMS, have been pivotal in achieving major milestones. Additionally, Jack’s expertise in these areas has helped numerous pharmaceutical companies establish quality manufacturing frameworks.

Jack is an Organic Chemist by training and lives in Boston with his family.  In his spare time, he fixes broken things, cleans up messes, and combines these skills to restore vintage automobiles.